2. Biochemical Assay Reagents

Drug Delivery

Targeted Delivery Across Biological Barriers Prolonged Circulation Controlled Release
FAQ

Drug Delivery systems (DDS) can deliver drugs to the target location at the right time, improving drug bioavailability while reducing drug toxicity.

MCE offers 500+ drug delivery reagents, including multiple lipids, functionalized PEG, polymers, and lipid nanoparticles.

Biochemical Assay Reagents (3329):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-112251
    D-Lin-MC3-DMA 1224606-06-7 ≥98.0%
    D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
    D-Lin-MC3-DMA
  • HY-138170
    ALC-0315 2036272-55-4 ≥98.0%
    ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.
    ALC-0315
  • HY-101103
    HP-β-CD 128446-35-5 99.74%
    HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability.
    HP-β-CD
  • HY-134541
    SM-102 2089251-47-6 ≥98.0%
    SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines.
    SM-102
  • HY-N0322
    Cholesterol 57-88-5 ≥98.0%
    Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
    Cholesterol
  • HY-B2247
    PLGA (50:50) 34346-01-5 ≥99.0%
    PLGA (50:50) (poly(lactic-co-glycolic acid) (50:50)) is a copolymer of poly lactic acid (PLA) and poly glycolic acid (PGA) which can be used to fabricate devices for drug delivery and tissue engineering applications.
    PLGA (50:50)
  • HY-112754A
    DOTAP chloride 132172-61-3 ≥98.0%
    DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid.
    DOTAP chloride
  • HY-138300
    ALC-0159 1849616-42-7 ≥98.0%
    ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient.
    ALC-0159
  • HY-N0322A
    Cholesterol (Water Soluble)
    Cholesterol Water Soluble can be used for the research of the effects of cholesterol on the potassium currents in inner hair cells (IHCs). Cholesterol is an integral component of the cell membrane and regulates the activity of ion channels in the lipid bilayer.
    Cholesterol (Water Soluble)
  • HY-112005
    DOPE 4004-05-1 ≥98.0%
    DOPE (dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA.
    DOPE
  • HY-112764
    DMG-PEG 2000 160743-62-4 ≥98.0%
    DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles.
    DMG-PEG 2000
  • HY-145405
    C12-200 1220890-25-4 ≥98.0%
    C12-200 is an ionizable cationic lipid and auxiliary lipid. C12-200 is commonly used for mRNA delivery. Administration of human erythropoietin (EPO) mRNA or factor VII siRNA increased and decreased serum factor VII levels, respectively, in LNPs mice containing C12-200.
    C12-200
  • HY-B0633A
    Hyaluronic acid 9004-61-9
    Hyaluronic acid (corn fermented) is a biopolymer composed of repeating units of disaccharides with various applications.
    Hyaluronic acid
  • HY-W040193
    DSPC 816-94-4 ≥98.0%
    DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
    DSPC
  • HY-112758
    DLin-KC2-DMA 1190197-97-7 ≥98.0%
    DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies.
    DLin-KC2-DMA
  • HY-109506
    DPPC 63-89-8 ≥98.0%
    DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice.
    DPPC
  • HY-113424A
    1,2-Dioleoyl-sn-glycero-3-phosphocholine 4235-95-4 ≥98.0%
    1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.
    1,2-Dioleoyl-sn-glycero-3-phosphocholine
  • HY-125853
    Phosphatidylcholines,soya 97281-47-5 ≥98.0%
    Phosphatidylcholines,soya is a phosphatidylcholine from soybean used in the preparation of liposomes. Phosphatidylcholines,soya can be used as a vehicle in animal agent administration.
    Phosphatidylcholines,soya
  • HY-140739
    DSPE-PEG2000-Maleimide
    DSPE-PEG2000-Maleimide is a PEG compound which composed of DSPE and maleimide groups. DSPE-PEG2000-Maleimide can be used for compose liposomes.
    DSPE-PEG2000-Maleimide
  • HY-142979
    DSPE-PEG 2000 892144-24-0
    DSPE-PEG 2000 is a PEG-lipid that can be used to form micelles as nanoparticles for drug delivery.
    DSPE-PEG 2000